n CME : Your SA Journal of CPD - Blunt head injury with diffuse brain damage or diffuse traumatic brain injury : main article
|Article Title||Blunt head injury with diffuse brain damage or diffuse traumatic brain injury : main article|
|© Publisher:||Health and Medical Publishing Group (HMPG)|
|Journal||CME : Your SA Journal of CPD|
|Publication Date||Mar 2006|
|Pages||122 - 126|
|Keyword(s)||Aetio-pathogenesis, Blunt head injury, Diffuse brain damage, Diffuse traumatic brain injury, Forensic neuropathological examination and Pathomorphology|
Mechanisms are complex and variable but include acceleration-deceleration and rotation of the head. <BR>The clinical state of concussion / coma is correlative. <BR>The macroscopic stigmata (imaging / autopsy) are haemorrhagic and evanescent, but brain may be macroscopically normal. <BR>The superficial macroscopic lesions are contusions; deep lesions are tissue tears. The microscopic lesions are microhaemorrhages, axonal spheroids and macrophage aggregates; lesions are evanescent. <BR>The distribution of microlesions is variable, with favoured sites, but should be widespread or 'diffuse' in diffuse brain injury. <BR>Diffuse microlesions can occur independently of brain swelling and vice versa. <br>Axonal spheroids are not specific; ischaemia is the commonest cause of these lesions. <BR>CT / MR is diagnostic, with gradient echo an essential technique, especially for follow-up / medico-legal purposes.
Article metrics loading...