n CME : Your SA Journal of CPD - Therapeutic challenges : interactions between anticonvulsants and antiretrovirals : clinical pharmacology
|Article Title||Therapeutic challenges : interactions between anticonvulsants and antiretrovirals : clinical pharmacology|
|© Publisher:||Health and Medical Publishing Group (HMPG)|
|Journal||CME : Your SA Journal of CPD|
|Author||Tamara Kredo and Gary Maartens|
|Publication Date||Sep 2006|
|Pages||528 - 530|
Extracted from text ... Case report A 36-year-old HIV-infected woman presents for assessment for antiretroviral therapy. As her current CD4+ count is 92 cells/mm3, she needs to commence antiretroviral therapy. She has a history of epilepsy since childhood, for which she receives treatment with carbamazepine. This case raises some important questions: Does this patient still require anticonvulsant therapy? What potential drug interactions could occur with antiretrovirals? Where there is a known primary focus, stopping anticonvulsants has a high rate of relapse. In a patient with idiopathic epilepsy, who has had no seizures for at least 2 years, slow weaning from the anticonvulsants can ..
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