n CME : Your SA Journal of CPD - Glaucoma

Volume 25, Issue 10
  • ISSN : 0256-2170



Glaucoma, a major cause of worldwide irreversible blindness, is a progressive optic neuropathy that is characterised by specific structural changes to the optic nerve head and associated functional (visual field) changes. This particular neuropathy involves apoptosis of the retinal ganglion cells whose axons comprise the optic nerve. The pathogenesis of this apoptosis is poorly understood, but it is thought to be a cascade set in motion by mechanical factors (elevated intraocular pressure (IOP)) or vascular factors or a combination of these two factors.

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