Full text loading...
n CME : Your SA Journal of CPD - Modern imaging in patients with obstructive jaundice : main article
- Cholestatic jaundice caused by intrahepatic hepatocellular disease may be clinically and biochemically indistinguishable from cholestasis due to extrahepatic bile duct obstruction.
- The most common intrahepatic causes of jaundice are viral hepatitis, alcohol-induced hepatitis, cirrhosis and drug-induced jaundice.
- Extrahepatic jaundice is most often due to a stone in the common bile duct or a pancreaticobiliary malignancy. Pancreatic pseudocysts, chronic pancreatitis, sclerosing cholangitis, benign bile duct strictures or parasites in the bile duct are less common causes.
- Ultrasound is a useful initial investigation because it is non-invasive and assesses pancreaticobiliary structures in real-time without exposing the patient to ionising radiation.
- Dilated ducts are indirect evidence of biliary obstruction.
- If bile ducts are not dilated, hepatocellular disease is the likely diagnosis; however, parenchymal liver disease or sclerosing cholangitis may prevent biliary dilatation despite obstruction being present.
Article metrics loading...