1887

n CME : Your SA Journal of CPD - Metformin and lactic acidosis : clinical pharmacology

USD

 

Abstract

  • Metformin-associated lactic acidosis is extremely rare.
  • Prospective studies have so far failed to demonstrate that the traditional contraindications increase the risk of this life-threatening complication.
  • Case reports have suggested that renal dysfunction may be the strongest association with this disorder.
  • A creatinine level greater than 130 mmol/ l in men and 120 mmol/ l in women has been suggested as a contraindication, but an estimation of the creatinine clearance is more meaningful.

Loading

Article metrics loading...

/content/m_cme/25/8/EJC63354
2007-08-01
2016-12-07
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error