n CME : Your SA Journal of CPD - Drugs and the older person : main article

Volume 25, Issue 9
  • ISSN : 0256-2170



Persons aged 60 years and over are the main consumers of drugs because of increased pathology requiring multiple medications. No local data are available but USA data show that while older persons constitute 13% of that country's total population, they consume approximately 35% of all medications used. Ageing alters pharmacokinetics (absorption, distribution, metabolism and elimination) and pharmacodynamics (drug-receptor or drug-organ interactions), which affects choice, dose and dosing frequency of many drugs.

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