n CME : Your SA Journal of CPD - Mind, immunity and health - the science and clinical application of psychoneuroimmunology : main article

Volume 26, Issue 1
  • ISSN : 0256-2170



  • Psychoneuroimmunology (PNI) is a multidisciplinary field spanning immunology, psychology and neuro-endocrinology.
  • The bi-directional communication occurs between the brain, endocrine and immune systems reflects a functional 'psychosomatic network'.
  • Chronic stress influences all aspects of the psychosomatic network.
  • Various psychosocial factors impact on immunity and resistance, their impact depends on the resilience of the individual who encounters these factors.
  • Hardiness, self-complexity and balanced emotional expression are important buffers against stress and immune dysfunction.
  • Mood, adaptive coping, continued life involvement, emotional processing, social support, doctor-patient relationship and spirituality, are all variables that can influence disease progression from a PNI perspective.
  • Managing stress, identifying relevant psychosocial factors and promoting self-efficacy, optimism and resilience is an important facet of comprehensive health care.

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