n CME : Your SA Journal of CPD - Anaemia of chronic disease

Volume 26, Issue 5
  • ISSN : 0256-2170



Anaemia of chronic disease (ACD) is a multifactorial anaemia often coexistent with iron deficiency. Worldwide, anaemia of chronic disease is the second most common anaemia. Diagnosis generally requires the presence of chronic infection, inflammation, or cancer; marginal normocytic and later microcytic anaemia; and abnormal values for iron studies. The major issue is that the bone marrow erythroid mass fails to expand appropriately in response to anaemia. Treatment is to reverse the underlying disease and, if the disease is irreversible, to give erythropoietin.

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