n CME : Your SA Journal of CPD - A clinical approach to dyslipidaemia
|Article Title||A clinical approach to dyslipidaemia|
|© Publisher:||Health and Medical Publishing Group (HMPG)|
|Journal||CME : Your SA Journal of CPD|
|Author||Dirk J. Blom|
|Publication Date||Mar 2009|
|Pages||108 - 114|
Life as we currently know it could not exist without lipids. For example, the much-maligned cholesterol molecule plays critical roles in membrane organisation, signal transduction, bile acid and steroid hormone synthesis - and these are just a few of its many roles. The critical importance of cholesterol is underscored by the large number of genes that regulate its metabolism and the devastating clinical consequences of the (luckily) very rare disorders in which 'abnormal' sterol molecules accumulate or cholesterol synthesis is disrupted. Yet excessive circulating cholesterol is an important contributor to atherosclerosis, which is the leading cause of deathin the developed world and rapidly increasing in the developing world.
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