n CME : Your SA Journal of CPD - Lower-limb venous thrombosis




Deep-vein thrombosis (DVT) and pulmonary embolism (PE) are major causes of significant morbidity and mortality which are frequently, but not exclusively, associated with surgery, injury and other reasons for hospitalisation. In the acute setting, PE may be fatal while in the long term pulmonary hypertension can develop, particularly from recurrent PE. Post-thrombotic chronic venous insufficiency, better described as post-phlebitic chronic lower-limb venous hypertension (CVH), occurs as a result of the DVT causing deep venous reflux and/or venous outflow obstruction and can cause swelling, skin changes (dermatoliposclerosis) and venous ulceration. With appropriate therapy the risk of both the primary condition as well as the consequences thereof can be reduced. As DVT and PE are inextricably linked the syndrome is usually referred to as venous thromboembolism (VTE).


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