n CME : Your SA Journal of CPD - Common adverse drug reactions with psychiatric medications and an approach to their management : main article




Adverse drug reactions are defined as an 'unexpected, unintended, undesired or excessive response to a drug', which would include 'allergic reactions and idiosyncratic reactions that are an abnormal susceptibility to a drug peculiar to the individual'. It is important to understand that psychiatric medications, as with medication generally (including non-prescription compounds, e.g. St John's Wort), carry a risk of adverse reactions. For example, a major concern with St John's Wort is that of interactions with conventional drugs, including selective serotonin reuptake inhibitors, due to induction of the cytochrome 'P450 enzyme system. '


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