n CME : Your SA Journal of CPD - Use of biological agents in rheumatic disease : more about rheumatology

Volume 29, Issue 8
  • ISSN : 0256-2170



In a large number of rheumatic diseases the disease process is driven by the immune system. In the past few decades, there have been great advances in our understanding of the immunopathology and pathogenesis of the rheumatic diseases. At the same time, there have been similar advances in the development of drugs, particularly in the field of biopharmaceutical drugs that can target specific components of the immune response central to these diseases. Biological drugs can be monoclonal antibodies or proteins produced by living cells that bind with receptors on various cells to block formation or action of various cytokines or cell mediators, or in other ways change cell function.

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