n CME : Your SA Journal of CPD - Neurological complications of HIV / AIDS in childhood : main article




The neurological manifestations of AIDS may result from direct neuronal infection, the cytokine-mediated effects of the virus and immune dysregulation. The spectrum of neurological manifestations of the disease is diverse. However, most published data relate to HIV encephalopathy (HIVE), with less focus on other complications, i.e. cerebrovascular disease, epilepsy and peripheral neuropathy. The advent of triple antiretroviral therapy has led to improved survival of HIV-infected children and an increasing recognition of these other complications in the paediatric population.


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