n CME : Your SA Journal of CPD - Thyroid disease : thyroid function tests and interpretation




Diseases of the thyroid are among the most prevalent of medical conditions, especially in women, but the symptoms can be relatively nonspecific or mild. For this reason, clinicians have been placing increased reliance on the laboratory for assistance in the diagnosis of thyroid disorders. In the 1950s, only one thyroid test was available, the protein-bound iodine estimate of the serum total thyroxine (T4) concentration which showed a poor sensitivity and specificity for thyroid disease.


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