n CME : Your SA Journal of CPD - Biomarkers and genes predictive of disease predisposition and prognosis in rheumatoid arthritis




Rheumatoid arthritis (RA) is a debilitating disease that affects the articular joints of patients. The prognosis of the disease varies from mild cartilage degradation to progressive erosive disease of the juxta-articular bone. Progression may be cyclical or unremitting and often severity entails extra-articular manifestations such as RA nodules and vasculitis. A spontaneous remission is observed in 10 - 20% of patients while the majority of the patients progress to relentless severe disease.


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