n CME : Your SA Journal of CPD - Barrett's oesophagus : more about




Barrett's oesophagus (BO) is defined as the occurrence of metaplastic, specialised columnar epithelium lining the distal part of the oesophagus. Evidence points to this as a metaplastic condition in reaction to ulceration and re-epithelialisation, the columnar epithelium replacing the normal stratified squamous epithelium. Only specialised columnar epithelium consisting of a villiform growth pattern containing columnar, goblet, Paneth and endocrine cells (i.e. intestinal metaplasia (IM)) located above the lower oesophageal sphincter (LOS) qualifies as BO.


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