n CME : Your SA Journal of CPD - Barrett's oesophagus : more about
|Article Title||Barrett's oesophagus : more about|
|© Publisher:||Health and Medical Publishing Group (HMPG)|
|Journal||CME : Your SA Journal of CPD|
|Affiliations||1 National Health Laboratory Service (NHLS) and 2 University of Pretoria|
|Publication Date||Feb 2013|
|Pages||53 - 54|
Barrett's oesophagus (BO) is defined as the occurrence of metaplastic, specialised columnar epithelium lining the distal part of the oesophagus. Evidence points to this as a metaplastic condition in reaction to ulceration and re-epithelialisation, the columnar epithelium replacing the normal stratified squamous epithelium. Only specialised columnar epithelium consisting of a villiform growth pattern containing columnar, goblet, Paneth and endocrine cells (i.e. intestinal metaplasia (IM)) located above the lower oesophageal sphincter (LOS) qualifies as BO.
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