oa Journal of Endocrinology, Metabolism and Diabetes in South Africa - Tumour-induced osteomalacia : a curable condition : case report

Volume 14, Issue 3
  • ISSN : 1608-9677
  • E-ISSN: 2220-1009



Osteomalacia is a condition characterised by failure of bone mineralisation. While abnormalities of vitamin D supply, metabolism or action are the most common and well-known causes, chronic phosphate deficiency, due to either insufficient input (intake or absorption) or renal losses are also important causes of rickets or osteomalacia. Hypophosphataemia also commonly co-exists with vitamin D deficiency, pursuant to secondary hyperparathyroidism. Other causes include chronic calcium deficiency, hypophosphatasia, fluoride and aluminium excess.

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