oa Journal of Endocrinology, Metabolism and Diabetes in South Africa - Pregnancy- and lactation-associated osteoporosis : case study

Volume 17, Issue 3
  • ISSN : 1608-9677
  • E-ISSN: 2220-1009



Pregnancy- and lactation-associated osteoporosis is a rare syndrome of spontaneous fractures occurring in late pregnancy or lactation. Early diagnosis and management is essential, because of the severity of the morbidity associated with these fractures. Prior to therapy, other reversible causes of osteoporosis should be excluded through adequate investigation. Treatment includes cessation of breastfeeding, the provision of adequate pain relief, and the use of specific osteoporosis drugs, preferably those with short-term bone retention. Although there is no persuasive evidence that calcium and vitamin D requirements increase during pregnancy or lactation compared to the non-pregnant woman of childbearing age, it is advisable to ensure that women are vitamin D replete during pregnancy and lactation.

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