oa Journal of Endocrinology, Metabolism and Diabetes in South Africa - Autoimmune polyglandular syndrome type 1 in a 12-year-old Ugandan girl : case study
|Article Title||Autoimmune polyglandular syndrome type 1 in a 12-year-old Ugandan girl : case study|
|© Publisher:||Medpharm Publications|
|Journal||Journal of Endocrinology, Metabolism and Diabetes in South Africa|
|Affiliations||1 Makerere University, Uganda, 2 Makerere University, Uganda, 3 Mulago National Referral and Teaching Hospital, Uganda and 4 Mulago National Referral and Teaching Hospital, Uganda|
|Publication Date||Jan 2013|
|Pages||65 - 67|
|Keyword(s)||APS-1, Autoimmune diseases, Autoimmune polyglandular syndrome type, Chronic hypoparathyroidism and Chronic mucocutaneous candidiasis|
Autoimmune polyglandular syndrome type 1 (APS-1), also known as autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy syndrome, is a very rare disorder of childhood. It is mainly characterised by the presence of at least two of the following: chronic mucocutaneous candidiasis, chronic hypoparathyroidism and autoimmune Addison's disease. We report on the case of a 12-year-old Ugandan female patient who presented with features that were most consistent with APS-1 (chronic mucocutaneous candidiasis and hypoparathyroidism). Significant clinical improvement was noted following oral antifungal therapy.
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