oa Journal of Endocrinology, Metabolism and Diabetes in South Africa - Population differences in parameters of bone and mineral metabolism - the African fracture paradox : editorial



Extracted from text ... The World Health Organisation (WHO)'s definition of osteoporosis is based on the relationship between low bone mineral density (BMD) and consequent increase in bone fragility and susceptibility to fracture.1 As such, a risk factor (i.e low BMD) has been elevated to assume the status of a diagnostic criterion.2 In South Africa, the incidence of osteoporosis in white, Asian and mixed-race populations appears to be similar to incidence rates in developed countries. Osteoporotic fractures are, however, 10 times less prevalent in our black populations,3 which is also the case in the USA.4 Whereas the lower prevalence of fractures in Afro- Americans is readily explained on the basis of an approximate 15% higher BMD ..


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