n Southern African Journal of Critical Care - Antibiotic therapy of surgical infections : current practice

Volume 26, Issue 1
  • ISSN : 1562-8264
  • E-ISSN: 2078-676X



We face a crisis with regard to antibiotic resistance. Highly pathogenic, pan-resistant Gram-negative (GN) or highly resistant Gram-positive (GP) infections are increasingly prevalent in the intensive care unit and in the general wards. Whereas no intervention will eradicate resistance, it is essential that antibiotic management be optimised both to improve efficacy and to extend the lifespan of drugs that are currently available.

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