n South African Journal of Child Health - Pneumococcal conjugate vaccine - advancing child health in South Africa : hot topics

Volume 2, Issue 3
  • ISSN : 1994-3032
  • E-ISSN: 1999-7671



Pneumococcal disease caused by is a major cause of death, hospitalisation and morbidity in children in South Africa and Africa. Paediatric pneumococcal disease manifests most commonly as otitis media, pneumonia or meningitis. Otitis media is commonest, occurring approximately 10 times more frequently than pneumonia and 100 times more than meningitis. However, pneumonia or meningitis are severe forms of disease, responsible for a large proportion of childhood mortality and morbidity. is the most important bacterial cause of pneumonia in children, responsible for 1 - 4 million episodes of pneumonia in Africa annually.

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