n South African Journal of Child Health - Preventing invasive Group B Streptococcus (GBS) disease in South African infants : time for change : editorial
|Article Title||Preventing invasive Group B Streptococcus (GBS) disease in South African infants : time for change : editorial|
|© Publisher:||Health and Medical Publishing Group (HMPG)|
|Journal||South African Journal of Child Health|
|Affiliations||1 University of the Witwatersrand, 2 University of the Witwatersrand, 3 University of the Witwatersrand and 4 National Institute for Communicable Diseases|
|Publication Date||Aug 2015|
|Pages||69 - 70|
Streptococcus agalactiae is an encapsulated Gram-positive coccus that colonises the gastrointestinal and genitourinary tracts. This organism belongs exclusively to Group B in Lancefield's grouping of Streptococcus species and therefore is referred to as Group B Streptococcus (GBS). Of the ten known serotypes, serotypes Ia and III account for most disease. The greatest burden of invasive GBS disease is seen in infants <3 months of age, although GBS can cause disease in adults and pregnant women. Disease manifesting in the first 6 days of life is referred to as early-onset disease (EOD), whereas late-onset disease (LOD) manifests from day 7 - 89 of life.
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