n Southern African Journal of HIV Medicine - Guidelines for antiretroviral therapy in adults : ART in adults

Volume 1, Issue 1
  • ISSN : 1608-9693
  • E-ISSN: 2078-6751



The magnitude of HIV infection in Southern Africa and the number of impoverished people who desperately need antiretroviral therapy (ART), but who will never receive this, is overwhelming, and unparalleled in the history of infectious diseases. High costs associated with antiretroviral therapy remain the most prohibitive factor influencing the way that HIV is managed in countries such as South Africa, where the availability of finance determines access to therapy. While the Southern African HIV Clinicians Society endorses the right of all HIV-infected adults and children to receive an optimal standard of care, it also acknowledges the serious limitations influencing individual access to effective therapy. As a result of the constraints within the Southern African context, treatment cannot always be optimal and this has resulted in serious contemplation of acceptable, yet not always optimal, therapeutic alternatives that may currently be more affordable and realistic. Certain recommendations in this document are therefore presented as unavoidable compromises that might not meet internationally established standards of care, and where these occur, they have been indicated by a grey shaded background. As knowledge and understanding of the use of antiretroviral therapies is still evolving and new therapeutic agents become available, these guidelines will be reviewed and updated regularly. The most current version should always be consulted.

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