n Southern African Journal of HIV Medicine - Tuberculosis and HIV/AIDS in South Africa : tuberculosis

Volume 1, Issue 2
  • ISSN : 1608-9693
  • E-ISSN: 2078-6751



Nearly two-thirds of South Africa's population has at some time been infected with Mycobacterium tuberculosis. Mast people do not develop symptoms and become clinically ill as they have a robust immune response sufficient to contain the organism's replication. Of the 30% of affected people who develop infections, about 5% develop clinical or active disease, located principally in the lung. Well-known South Africans such as Archbishop Desmond Tutu and the former President Nelson Mandela were once afflicted with tuberculosis (TB). South Africa, like the rest of southern Africa, is experiencing concurrent explosive epidemics of HIV and TB. Indeed, TB is the most frequent opportunistic infection, leading to a number of deaths among HIV-infected patients in sub-Saharan Africa.

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