n Southern African Journal of HIV Medicine - Cavitation of the Ghon focus in an HIV-infected infant who acquired tuberculosis after the initiation of HAART : paediatric case study

Volume 10, Issue 1
  • ISSN : 1608-9693
  • E-ISSN: 2078-6751



Tuberculosis immune reconstitution inflammatory syndrome (IRIS) may present as new or worsening cavitation. We present an HIV-infected infant in whom TB infection and subsequent cavitation of the Ghon focus appeared to coincide with immune reconstitution due to highly active antiretroviral therapy (HAART). TB-IRIS in response to infection that occurs after starting HAART has not previously been described.

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