n Southern African Journal of HIV Medicine - Infant feeding and HIV : review

Volume 10, Issue 4
  • ISSN : 1608-9693
  • E-ISSN: 2078-6751



Recent studies on antiretroviral prophylaxis during breastfeeding show that maternal highly active antiretroviral therapy (HAART) (alone or with 1, 4 or 24 weeks' infant prophylaxis) or infant prophylaxis alone for 6, 14 or 24 weeks (with limited maternal prophylaxis) reduces HIV transmission through breastmilk (postnatal transmission). Maternal postnatal regimens appear to be as efficacious as infant postnatal regimens, although one study shows a trend favouring infant nevirapine over maternal HAART (both used from 1 week to 6 months after delivery). These new findings necessitate a review of existing interventions to prevent mother-to-child transmission of HIV (PMTCT) , and the immediate implementation of regimens that reduce postnatal transmission - where this is feasible - to save children's lives.

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