n Southern African Journal of HIV Medicine - Cervical cancer prevention in settings of high HIV prevalence : opinion
|Article Title||Cervical cancer prevention in settings of high HIV prevalence : opinion|
|Journal||Southern African Journal of HIV Medicine|
|Publication Date||Jun 2011|
|Pages||18 - 20|
|Keyword(s)||London School of Hygiene and Tropical Medicine Alumni|
Despite being a preventable disease, cervical cancer is still the second most common cancer in women worldwide. HIV infection is associated with a higher incidence, more rapid progression, and increased recurrence rates of human papillomavirus (HPV)-associated cervical intra-epithelial neoplasia and invasive cancer. The disease burden in developing countries is the result of inadequate national health care infrastructures that cannot establish or sustain comprehensive screening programmes, together with a high prevalence of HIV infection, particularly in southern Africa. In this article, clinically relevant issues for primary prevention of cervical lesions by a quadrivalent HPV vaccine and the 'screen-and-treat' protocol in settings of high HIV prevalence will be explored.
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