n Southern African Journal of HIV Medicine - Progressive HIV infection in the presence of a raised CD4+ count : HIV/HTLV-1 co-infection : case report
|Article Title||Progressive HIV infection in the presence of a raised CD4+ count : HIV/HTLV-1 co-infection : case report|
|Journal||Southern African Journal of HIV Medicine|
|Affiliations||1 University of Pretoria, 2 University of Pretoria and 3 National Health Laboratory Service|
|Publication Date||Jun 2013|
|Pages||92 - 94|
There are a number of pathophysiological causes for a normal or raised CD4 count in the context of progressive HIV infection. These include various co-infections, previous splenectomy, and lymphoproliferative disorders. Such circumstances can both confound HIV diagnosis and delay initiation of chemoprophylaxis and highly active antiretroviral therapy (HAART). We describe the case of a patient co-infected with HIV and human T-cell lymphotropic virus type 1 (HTLV-1) who, prior to HAART initiation, was found to have progressive immune deficiency associated with a raised CD4 count.
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