n Southern African Journal of HIV Medicine - Metabolic disorders in the HAART era : conference report
|Article Title||Metabolic disorders in the HAART era : conference report|
|Journal||Southern African Journal of HIV Medicine|
|Publication Date||Jan 2001|
|Pages||6 - 13|
Despite an abundance of data in recent months, a case definition for lipodystrophy has not yet been determined, nor have the pathogenesis and aetiology been elucidated. Complicating this is the wide array of clinical observations and cause-related hypotheses - often in conflict with each other - that have been made by many researchers the world over. Two important recurring themes suggest that the problem needs a multifactorial approach and that it might indeed involve multiple syndromes, both directly and indirectly related to antiretroviral therapy (ARD. These two caveats are that there appear to be gender differences, and that metabolic differences and body habitus changes do not uniformly coexist in all patients classified as having lipodystrophy.
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