1887

n Southern African Journal of HIV Medicine - Antiretroviral therapy in adults : March 2005 : guidelines

USD

 

Abstract

Sub-Saharan Africa has just over 10% of the world's population but is home to more than 60% of all people living with HIV (approximately 25.4 million people). Prevalence rates in southern Africa's antenatal clinics surpass 25%, the highest in the world. <br>South Africa is host to the highest number of HIV-infected people in the world (5.3 million, UNAIDS/WHO AIDS epidemic update, December 2004) with considerable regional variation and an annual increase in all but two provinces (Free State and Gauteng). The Free State, Mpumalanga and KwaZulu-Natal have prevalence rates among pregnant women attending public sector antenatal clinics of > 30% while the remaining provinces have a range of between 15% and 17.5%. <br>Four other countries in the region have very high antenatal prevalence rates, often exceeding 40%: Botswana, Lesotho, Namibia and Swaziland (39%). Elsewhere in the sub-region HIV infections in pregnant women appear to be stabilising at lower levels, e.g. Malawi (18%), Zambia (16%) and Zimbabwe (25%). Uganda's prevalence, though still high, has dropped in the last decade to 5 - 6%. Angola is the exception in the region, having had very low prevalence levels for some years, possibly owing to the war which restricted civilian movement. Prevalence remains at about 3% at Luanda's antenatal clinics; however, sex workers have an incidence of 33%, fuelling fears of a widespread and rapid spread in this country. <br>Most sub-Saharan countries have antiretroviral roll-outs, albeit at different stages and levels of delivery. <br>In July 2004, the Health Systems Trust, reported in the first <I>South African Health Review (SAHR)&lt;/I&gt; that AIDS was responsible for 39% of deaths in South Africa in 2000. Gearing up for the national antiretroviral (ARV) roll-out in early 2003, the South African government estimated that about half a million South Africans with AIDS were in urgent need of ARV treatment (ART). In March 2003 the Department of Health commenced the national roll-out at a handful of pre-selected, designated pilot sites, aiming to treat 53 000 HIV-infected South Africans (CD4+ counts of < 200/µl) with ARVs by March 2004, and expanding the number of sites over time. To date progress has been slower than planned. National ART guideline regimens are advised in these guidelines.

Loading

Article metrics loading...

/content/m_sajhiv/2005/18/EJC65320
2005-03-01
2016-12-03
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error