n Southern African Journal of HIV Medicine - HIV-discordant couples : an emerging issue in prevention and treatment : discordant couples

Volume 2006, Issue 23
  • ISSN : 1608-9693
  • E-ISSN: 2078-6751



Extracted from text ... 25 An increasingly encountered phenomenon in research and clinical management of HIV is HIV discordance, the situation where one member of a sexual partnership is HIV infected, while the other is uninfected. This situation has wide clinical and research implications. In particular, seronegative partners within discordant relationships are a particularly high-risk group for HIV acquisition; a high proportion of new HIV infections in mature generalised epidemics is likely to occur within discordant couples.1 In this overview we will examine some of the biological and socio-behavioural correlates of discordance. As identification of the joint serostatus of a couple poses particular ..

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