n Southern African Journal of HIV Medicine - Drug interactions with antiretroviral therapy : drug interactions

Volume 3, Issue 3
  • ISSN : 1608-9693
  • E-ISSN: 2078-6751



HIV-infected patients are often prescribed multiple drugs : for prophylaxis of opportunistic infections, as antiretroviral medication, for side-effects of medication, and to treat concomitant illnesses, both acute and chronic. Patients may seek medical care from more than one practitioner or health care facility, and often do not actively volunteer information about their HIV status or current medication, including antiretrovirals. In addition, many patients make use of over-the-counter and traditional or herbal remedies, as well as illicit and recreational drugs, often without consulting their health care givers. As access to antiretroviral therapy expands in South Africa, the potential for drug interactions with antiretrovirals becomes increasingly important to prescribers.

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