n Southern African Journal of HIV Medicine - Abacavir in children : Abacavir

Volume 3, Issue 3
  • ISSN : 1608-9693
  • E-ISSN: 2078-6751



Abacavir (ABC) (Ziagen) is a new nucleoside analogue reverse transcriptase inhibitor (NRTI). It has already been registered with the Medicines Control Council and should be launched some time in 2003. At present it is available on a named-patient basis from GlaxoSmith Kline. In contrast with the other NRTls, ABC is a quanosine antagonist.

Although the data on ABC in children are limited, there are a number of features of ABC that make it a useful drug in the antiretroviral arsenal. Conversely, as with all medications, there are some negative features that must be taken into account.

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