n Southern African Journal of HIV Medicine - Case study - a second opinion on management




Patients diagnosed with tuberculosis (TB) and then commenced on antiretroviral therapy (ART) are often on several drugs that can cause a hypersensitivity drug reaction. Such reactions may take the form of a drug rash (which may evolve to a Stevens-Johnson syndrome or toxic epidermal necrolysis), hepatitis, a drug fever or a combination of these. These reactions result in considerable morbidity directly and indirectly because they cause interruptions in optimal treatment for the TB and HIV.


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