n South African Journal of Obstetrics and Gynaecology - The Magpie study - clinical implications for poor countries : clinical practice




Extracted from text ... SAJOG 9 February 2004, Vol. 10, No. 1 SAJOG The results of the Magpie Trial, a double-blind randomised controlled trial to assess the role of magnesium sulphate (MgSO4) in preventing eclampsia in women with preeclampsia, were published recently.1 Several South African units were among the 175 hospitals from 33 participating countries. In total, 2 678 of the 10 123 women recruited came from this country. The incidence of eclampsia in the study was 1.9% in the placebo group, compared with 0.8% among women randomised to receive MgSO4. Risk reduction represents a risk reduction of 59%. Put differently, it means that 1 case of eclampsia will be prevented for every 91 women with ..


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