n South African Journal of Obstetrics and Gynaecology - Increased oxidative stress in Nigerian women with pre-eclampsia : scientific letter
|Article Title||Increased oxidative stress in Nigerian women with pre-eclampsia : scientific letter|
|© Publisher:||Health and Medical Publishing Group (HMPG)|
|Journal||South African Journal of Obstetrics and Gynaecology|
|Author||K.S. Adedapo, O. Olayemi, A.A. Odukogbe, C.O. Aimakhu, A.O. Kehinde and B.L. Salako|
|Publication Date||May 2011|
|Pages||50 - 51|
|Keyword(s)||University College Hospital|
To the Editor: The precise causation of pre-eclampsia is still unknown, but oxidative stress in pre-eclampsia is well documented. In pre-eclampsia, antioxidant capacity has been shown to be decreased in the placenta and serum. However, some workers have questioned the role of oxidative stress and lipid peroxidation in pre-eclampsia. Furthermore, two randomised controlled trials of antioxidant supplementation during pregnancy with vitamin C and E showed no prophylactic or protective effect on the incidence of pre-eclampsia.
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