n South African Journal of Obstetrics and Gynaecology - Increased oxidative stress in Nigerian women with pre-eclampsia : scientific letter

Volume 17, Issue 2
  • ISSN : 0038-2329
  • E-ISSN: 2078-5135



: The precise causation of pre-eclampsia is still unknown, but oxidative stress in pre-eclampsia is well documented. In pre-eclampsia, antioxidant capacity has been shown to be decreased in the placenta and serum. However, some workers have questioned the role of oxidative stress and lipid peroxidation in pre-eclampsia. Furthermore, two randomised controlled trials of antioxidant supplementation during pregnancy with vitamin C and E showed no prophylactic or protective effect on the incidence of pre-eclampsia.

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