n South African Journal of Obstetrics and Gynaecology - Sensitivity and specificity of the human papillomavirus identification test : scientific letter

Volume 17, Issue 3
  • ISSN : 0038-2329
  • E-ISSN: 2078-5135



When the sensitivity of a test such as the Pap smear is determined, both positive and negative results should be submitted to the gold standard of histology. If this is not done, the sensitivity will be unrealistically high. The human papillomavirus (HPV) test has not been adequately investigated in this way. In this letter I report a preliminary study in which the HPV test was evaluated against histology in all cases.

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