n South African Journal of Obstetrics and Gynaecology - A review of the incidence and survival of childhood and adolescent cancer and the effects of treatment on future fertility and endocrine development : review

Volume 18, Issue 2
  • ISSN : 0038-2329
  • E-ISSN: 2078-5135



Cancer is not uncommon in children. The reproductive system is an important site for late effects of cancer treatment, and normal pubertal development depends on an undamaged hypothalamic-pituitary-gonadal axis. Fertility compromise can occur due to chemotherapy, radiotherapy to the hypothalamic-pituitary-gonadal axis, or surgery. Cryopreservation techniques of germ cells are improving and may offer hope for fertility preservation.

Loading full text...

Full text loading...


Article metrics loading...


This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error