n South African Journal of Obstetrics and Gynaecology - A review of the incidence and survival of childhood and adolescent cancer and the effects of treatment on future fertility and endocrine development : review
|Article Title||A review of the incidence and survival of childhood and adolescent cancer and the effects of treatment on future fertility and endocrine development : review|
|© Publisher:||Health and Medical Publishing Group (HMPG)|
|Journal||South African Journal of Obstetrics and Gynaecology|
|Affiliations||1 Stellenbosch University, 2 Stellenbosch University, 3 Tygerberg Academic Hospital and 4 Tygerberg Academic Hospital|
|Publication Date||Jan 2012|
|Pages||48 - 53|
Cancer is not uncommon in children. The reproductive system is an important site for late effects of cancer treatment, and normal pubertal development depends on an undamaged hypothalamic-pituitary-gonadal axis. Fertility compromise can occur due to chemotherapy, radiotherapy to the hypothalamic-pituitary-gonadal axis, or surgery. Cryopreservation techniques of germ cells are improving and may offer hope for fertility preservation.
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