n South African Journal of Psychiatry - QT-prolonging drugs : should they ever be used? : editorial




Extracted from text ... 40 editorial Volume 11 No. 2 September 2005 - SAJP QT-prolonging drugs: Should they ever be used? Andrzej Okreglicki (Dr AO) trained at Groote Schuur Hospital, Newcastle, UK, and Rochester, NY, USA. His main interests are arrhythmias, interventional cardiology, rhythm devices and sudden cardiac arrest. If the current stringent conditions of bodies that register and control medicines had been in force for decades, many commonly used drugs (from antibiotics and antihistamines to antipsychotics and antiarrhythmics) would never have reached the consumer market. Nowadays, pre-release findings of QT prolongation are likely to scupper early-phase trials and result in the abandonment of ..


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