n South African Journal of Psychiatry - Orexin - does it have a role in mental illness?
|Article Title||Orexin - does it have a role in mental illness?|
|Journal||South African Journal of Psychiatry|
|Author||M.Y.H. Moosa and F.Y. Jeenah|
|Publication Date||Jun 2008|
|Pages||63 - 64|
ISI Social Science
Orexin-A and Orexin-B (also known as hypocretin 1 and 2) are, respectively, 33- and 28-amino acid residue peptides that activate a G-protein-coupled 'orphan' receptor, i.e. which has no known ligand. Immuno-cytochemical studies show that orexin-positive neurons are located in the lateral hypothalamic area and arcuate and perifornical nuclei.
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