n SA Journal of Radiology - Multicentric epitheloid haemangioendothelioma of bone : case report

Volume 11, Issue 1
  • ISSN : 1027-202X
  • E-ISSN: 2078-6778



Multicentric epitheloid haemangioendothelioma (EHE) of bone is a rare primary bone tumour which may present at any age. The diagnosis is suspected on radiographs and the differential diagnosis includes metastatic disease, epitheloid angiosarcoma and EHE. Confirmation is only by means of biopsy and histological examination.

Multiple lesions and metastases are confirmed or excluded by further imaging such as radiographs, whole-body nuclear bone scan and CT scan of the chest. When positive, these findings change the prognosis and approach to treatment.
In our case an elderly man presented with a pathological fracture of the right tibia as a complication of EHE. Diagnosis was suspected on radiographs and confirmed on histology. Whole-body bone scintigraphy and CT scan of the chest were performed, which confirmed multiple bone lesions and metastases to the lungs.

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