n SA Journal of Radiology - Bilateral periventricular nodular heterotopia - neonatal cranial ultrasound : pictorial interlude

Volume 14, Issue 1
  • ISSN : 1027-202X
  • E-ISSN: 2078-6778



A female neonate was delivered at 30 weeks' gestation to a mother with suspected bilateral periventricular nodular heterotopia (PNH) on computed tomography brain scan. Antenatal ultrasound (US) performed at 28 weeks' gestation showed mild lateral cerebral ventricle dilatation, but no other fetal anomalies. Clinical examination revealed mild dysmorphic features: facial and skull asymmetry, square-shaped ears, and long tapering fingers. Chromosomal analysis showed a 46XX karyotype.

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