n SA Journal of Radiology - The enigma of reversible splenial lesions : case series

Volume 14, Issue 1
  • ISSN : 1027-202X
  • E-ISSN: 2078-6778



Focal reversible lesions of the splenium of the corpus callosum have been described in a number of clinical paradigms. Epilepsy and related conditions are the most commonly reported underlying clinical association. Sudden anti-epileptic therapy withdrawal or seizure activity may be presumed to be the predisposing cause. However, an individual susceptibility must also be considered. Although the exact mechanism producing this syndrome is not known, the MRI appearance and course in each of these clinically distinct causative entities is similar. The complete reversibility of the abnormality on follow-up studies is common to all, and many authors suggest that a conservative watchful approach is all that is required. We present here the findings in two patients with similar, completely reversible, splenial lesions.

Loading full text...

Full text loading...


Article metrics loading...


This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error