n South African Journal of Surgery - Acinar cell carcinoma - a rare tumour of the pancreas : case report

Volume 46, Issue 3
  • ISSN : 0038-2361
  • E-ISSN: 2078-5151



A 32-year-old man presented with a progressively enlarging, firm, non-tender abdominal mass, more prominent on the left. He was fit and had no significant past medical history. Routine blood tests were all normal (including liver functions, amylase and α-fetoprotein). A computed tomography (CT) scan showed a 10x13x11.5 cm well-defined, solid and cystic mass in the lesser sac, with no evidence of distant spread. At laparotomy, a distal pancreatectomy and splenectomy were performed with a satisfactory plane around the tumour allowing complete macroscopic excision. Histological results were consistent with a pure acinar cell carcinoma. After discussion at a multidisciplinary oncology clinic, he was placed on a trial of gemcitabine-based chemotherapy.

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