n South African Journal of Surgery - The role of surgery in an imatinib-resistant GIST liver secondary : case report

Volume 53, Issue 2
  • ISSN : 0038-2361
  • E-ISSN: 2078-5151



This is a case report describing the management of an imatinib-resistant liver secondary as a result of an exon 13 mutation. The gastric primary was completely excised 3 years prior and proven to contain an exon 11 mutation. Resective liver surgery was undertaken after the patient developed imatinib resistance and he has been disease-free for 19 months. The application of surgery in the context of other treatment options is discussed.

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