oa South African Journal of Sports Medicine - Stability of 19-norandrosterone and 19-noretiocholanolone glucuronide in urine under various storage conditions
|Article Title||Stability of 19-norandrosterone and 19-noretiocholanolone glucuronide in urine under various storage conditions|
|© Publisher:||Health and Medical Publishing Group (HMPG)|
|Journal||South African Journal of Sports Medicine|
|Affiliations||1 South African Doping Control Laboratory, Department of Pharmacology, University of the Free State, Bloemfontein|
|Publication Date||Jun 2003|
|Pages||14 - 17|
|Keyword(s)||Accuracy, Bacterial degradation, Chromatography, Derivatisation, Freeze and thaw stability, Hydrolysis, Liquid-liquid extraction, Long-term stability in freezer, Sample storage, Short term stability at room temperature, Solid phase extraction and Testing method|
The International Olympic Committee (IOC) has ruled that 19-norandrosterone should be quantified if present in low concentrations in urine of sport competitors. The question, however, is how stable is 19-norandrosterone in urine. In the light of this IOC ruling it is therefore important to know if the concentration of 19-norandrosterone can change during the transportation process of urine samples to the laboratory or during the handling and storage of the samples in the laboratory.
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