oa South African Journal of Sports Medicine - Position statement: Diabetes mellitus and exercise International Sports Medicine Federation (FIMS)
Diabetes mellitus is a common metabolic disease characterized by insulin insufficiency resulting in impaired ability to transport glucose across the cell membrane for its subsequent oxidation. Also, muscle and liver glycogen re synthesis, triglyceride synthesis in adipose cells, inhibition of their breakdown (antilipolytic effect), as well as protein synthesis and storage (anabolic effects) are being impaired. Insulin insufficiency thus leads to metabolic disturbances leading to such common symptoms as fatigue, weakness, weight loss, hunger, overeating, polyuria, and signs of glycosuria, and ketosis.
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