oa South African Journal of Sports Medicine - The influence of probenecid on the urinary excretion of androsterone
|Article Title||The influence of probenecid on the urinary excretion of androsterone|
|© Publisher:||Health and Medical Publishing Group (HMPG)|
|Journal||South African Journal of Sports Medicine|
|Affiliations||1 Department of Pharmacology, University of the Orange Free State, Bloemfontein|
|Publication Date||Aug 2000|
|Pages||16 - 20|
|Keyword(s)||Anabolic steroids, Apparatus, Calibration standards, Chromatograph-mass spectrometric method, Glucuronides, Peak plasma concentrations and Urine collections|
Objective: To determine the influence of probenecid on the urinary excretion of androsterone as a representative of anabolic-androgenic steroids. Design: Twenty healthy, male volunteers participated in an open, single-dose, randomised, two-way, cross-over study with a drug-free interval of 7 days between treatment phases. Each subject received either a placebo or a single dose of 2 000 mg (4 x 500 mg) probenecid tablets once in a randomised order.
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