oa South African Journal of Sports Medicine - Neural control mechanisms and anterior cruciate ligament injury

Volume 9, Issue 1
  • ISSN : 1015-5163
  • E-ISSN: 2078-516X



The anterior cruciate ligament (ACL) is a primary knee joint stabiliser preventing anterior tibial translation. Disruption of the ACL leads to an increased incidence of episodes of giving way of the affected limb, knee joint instability, and chronic quadriceps muscle atrophy. It was previously thought that this quadriceps muscle atrophy was a consequence of a relative disuse atrophy caused by post-injury immobilisation. However, recent work has shown that changes in activity in the muscles around the knee joint are regulated by neural mechanisms which are altered after disruption of the ACL.

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